2024

A Genetic Insight: Factor H-Related 1 in Atypical Hemolytic: Uremic Syndrome and C3 Glomerulopathy

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By: Amanda Slagle 

Presented at European Meeting on Complement in Human Disease (EMCHD)

Examining the Clinical and Complement Biomarker Profiles in C3 Glomerulopathy Patients Treated with Targeted Complement Inhibitors

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By: Lauren Fergus

Presented at European Meeting on Complement in Human Disease (EMCHD)

Functional Evaluation of Rare Variants in Complement Factor I using a Minigene Assay

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By: Cobey Donelson 

Presented at European Meeting on Complement in Human Disease (EMCHD)

Trends in Complement Pathway Biomarkers Before and After Eculizumab Initiation in C3 Glomerulopathy

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By: Tina Liu

Presented at European Meeting on Complement in Human Disease (EMCHD)

Histological and Complement Biomarker Correlations in C3 Glomerulopathy

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By: Jill Hall

Presented at Kidney Week - American Society of Nephrology

2023

Change in GFR and UPC Before and After Eculizumab in C3G

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By: Tina Liu 

Presented at Kidney Week – American Society of Nephrology (ASN)

Clinical and Histological Correlations in C3G

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By: Jill Hall

Presented at the International Complement Workshop (ICW)

The Functional Consequence of Two CFI Ultra Rare Variants in Complement-Mediated Diseases Insights from an In Vitro Splicing Assay

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By: Cobey Heinen

Presented at the International Complement Workshop (ICW)

Defining the Impact of Factor H, Factor H-related 1, and Factor H- related 5 on C3b Deposition on Human Glomerular Endothelial Cells

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By: Amanda Heiderscheit

Presented at the International Complement Workshop (ICW)

Function Analysis of Recombinant CFB Variants by ImmunoFixation Electrophoresis Assay

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By: Samantha Blain

Presented at the International Complement Workshop (ICW)

The Binding and Kinetics of Normal versus Pathogenic C3 Convertase Autoantibodies

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By: Christopher Culek

Presented at the International Complement Workshop (ICW)

Nephritic Factor-Like Autoantibodies are Present in Unaffected Children

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By: Christopher Culek 

Presented at Kidney Week – American Society of Nephrology (ASN)

2022

Predicting Post-Transplant Disease Recurrence in C3 Glomerulopathy

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By: Lauren Fergus

Presented at the European Meeting on Complement in Human Disease (EMCHD)

Copy Number Variations- A missing Genetic Driver in C3G

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By: Amanda Taylor

Presented at the European Meeting on Complement in Human Disease (EMCHD)

Elevated Factor H-related 1 and Factor H-related 5 Associate with End Stage Kidney Disease in C3 Glomerulopathy

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By: Amanda Heiderscheit 

Presented at the European Meeting on Complement in Human Disease (EMCHD)

The Importance of the Mg2+ Ion for Nephritic Factor Function

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By: Christopher Culek 

Presented at the European Meeting on Complement in Human Disease (EMCHD)

G6PD Deficiency: A Partner in Crime in Complement-Mediated Diseases or an “Innocent” Bystander?

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By: Nicolò Ghiringhelli Borsa

Presented at the International Pediatric Nephrology Association (IPNA) Congress  

Modeling C3 Glomerulopathies on ECM Surface

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By: Sofiya Pisarenka

Presented at Kidney Week – American Society of Nephrology (ASN)

Naturally Occurring C3-convertase Antibodies: A Nef Precursor?

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By: Christopher Culek 

Presented at Kidney Week – American Society of Nephrology (ASN)

Complement Factor I Variant in atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy

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By: Yuzhou Zhang

Presented at the International Society of Nephrology (ISN) conference

2021

Pregnancy Outcomes in C3G

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By: Lauren Fergus

Presented at Kidney Week – American Society of Nephrology (ASN)

Maturation of Decay Accelerating Activity Response Across the Natural History of C3 Glomerulopathy

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By: Christopher Culek

Presented at Kidney Week – American Society of Nephrology (ASN)

Functional Characterization of 105 Factor H Variants Associated with atypical HUS: Lessons for Variant Classification

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By: Hector Martin Merinero

Presented at Kidney Week – American Society of Nephrology (ASN)

2020

Clinical Biomarker Trend in C3G

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By: Monica Hall

Presented at Kidney Week – American Society of Nephrology (ASN)

Longitudinal Comparison of Nephritic Facto Stabilizing Activity in C3 Glomerulopathy

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By: Christopher Culek

Presented at Kidney Week – American Society of Nephrology (ASN)

Please appropriately cite the Molecular Otolaryngology and Renal Research Laboratories when including information from these posters and data. All content is copyrighted by the MORL at The University of Iowa.