2024
A Genetic Insight: Factor H-Related 1 in Atypical Hemolytic: Uremic Syndrome and C3 Glomerulopathy
By: Amanda Slagle
Presented at European Meeting on Complement in Human Disease (EMCHD)
Examining the Clinical and Complement Biomarker Profiles in C3 Glomerulopathy Patients Treated with Targeted Complement Inhibitors
By: Lauren Fergus
Presented at European Meeting on Complement in Human Disease (EMCHD)
Functional Evaluation of Rare Variants in Complement Factor I using a Minigene Assay
By: Cobey Donelson
Presented at European Meeting on Complement in Human Disease (EMCHD)
Trends in Complement Pathway Biomarkers Before and After Eculizumab Initiation in C3 Glomerulopathy
Histological and Complement Biomarker Correlations in C3 Glomerulopathy
2023
Change in GFR and UPC Before and After Eculizumab in C3G
Clinical and Histological Correlations in C3G
The Functional Consequence of Two CFI Ultra Rare Variants in Complement-Mediated Diseases Insights from an In Vitro Splicing Assay
Defining the Impact of Factor H, Factor H-related 1, and Factor H- related 5 on C3b Deposition on Human Glomerular Endothelial Cells
Function Analysis of Recombinant CFB Variants by ImmunoFixation Electrophoresis Assay
The Binding and Kinetics of Normal versus Pathogenic C3 Convertase Autoantibodies
Nephritic Factor-Like Autoantibodies are Present in Unaffected Children
By: Christopher Culek
Presented at Kidney Week – American Society of Nephrology (ASN)
2022
Predicting Post-Transplant Disease Recurrence in C3 Glomerulopathy
By: Lauren Fergus
Presented at the European Meeting on Complement in Human Disease (EMCHD)
Copy Number Variations- A missing Genetic Driver in C3G
By: Amanda Taylor
Presented at the European Meeting on Complement in Human Disease (EMCHD)
Elevated Factor H-related 1 and Factor H-related 5 Associate with End Stage Kidney Disease in C3 Glomerulopathy
By: Amanda Heiderscheit
Presented at the European Meeting on Complement in Human Disease (EMCHD)
The Importance of the Mg2+ Ion for Nephritic Factor Function
By: Christopher Culek
Presented at the European Meeting on Complement in Human Disease (EMCHD)
G6PD Deficiency: A Partner in Crime in Complement-Mediated Diseases or an “Innocent” Bystander?
By: Nicolò Ghiringhelli Borsa
Presented at the International Pediatric Nephrology Association (IPNA) Congress
Modeling C3 Glomerulopathies on ECM Surface
By: Sofiya Pisarenka
Presented at Kidney Week – American Society of Nephrology (ASN)
Naturally Occurring C3-convertase Antibodies: A Nef Precursor?
By: Christopher Culek
Presented at Kidney Week – American Society of Nephrology (ASN)
Complement Factor I Variant in atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy
Link to the poster
By: Yuzhou Zhang
Presented at the International Society of Nephrology (ISN) conference
2021
Pregnancy Outcomes in C3G
Maturation of Decay Accelerating Activity Response Across the Natural History of C3 Glomerulopathy
By: Christopher Culek
Presented at Kidney Week – American Society of Nephrology (ASN)
Functional Characterization of 105 Factor H Variants Associated with atypical HUS: Lessons for Variant Classification
By: Hector Martin Merinero
Presented at Kidney Week – American Society of Nephrology (ASN)
2020
Clinical Biomarker Trend in C3G
Longitudinal Comparison of Nephritic Facto Stabilizing Activity in C3 Glomerulopathy
By: Christopher Culek
Presented at Kidney Week – American Society of Nephrology (ASN)
Please appropriately cite the Molecular Otolaryngology and Renal Research Laboratories when including information from these posters and data. All content is copyrighted by the MORL at The University of Iowa.