Héctor Merinero, PhD
Postdoctoral Research Scholar (Renal)
About Me
During my research carrier I focused in understanding the pathogenic significance of complement genes variants in 2 rare renal diseases: atypical Hemolytic Uremic Syndrome (aHUS) and C3 Glomerulopathy (C3G). In this field I contributed with the largest functional characterization of disease-associated factor H (FH) variants, what allowed to stablish their association with the pathologies and to understand better the underlying mechanisms causing the diseases. I also contributed to find the mechanism associating a relatively common genetic rearrangement affecting the C-terminal regions of FH and FH related protein 1 (FHR-1) with aHUS. In this new stage in my carrier at the MORL I aim to keep helping to understand the genetic drivers behind these diseases, focusing on the FH related proteins and their surfaces ligands. I hope to be a valuable resource and contribute to the group.