MORL Screening Methodology

Targeted Sanger sequencing and/or next generation sequencing for detection of copy number variants previously identified in a family member on OtoSCOPE® panel testing.

(SEND ONLY ONE OF THE FOLLOWING SAMPLE TYPES) : 

  • 5µg DNA suspended in ≥ 50µl elution buffer
    • minimum concentration 50ng/µl
    • A260/A280 1.8-2.0
  • 3-5 cc EDTA Whole Blood
    • room temperature
  • Saliva
    • DNA Genotek, ORAGene Discover, OGR-500
  • Buccal Swabs 
    • at least 4 swabs
    • DNA Genotek, OraCollect, OCD-100

 

Click here to print sample and shipping requirements.

  • Whole Blood Sample Stability for DNA extraction
    • EDTA Whole Blood is stable for 7 days at room temperature and 4 months in the refrigerator
  • Saliva Collection Kits and Buccal Swabs Sample Stability
    • Per the manufacturer for samples collected following the instructions provided with kit/swabs: OGR-500 saliva collection kits are stable at room temperature for several years and OCD-100 buccal swabs stable up to 80 days.  Both of these kits can be shipped at room temperature.

  • Labeled with the sample type AND patient’s name, DOB, MRN and sex
  • Room temperature (DO NOT FREEZE)
  • Samples may be refrigerated if delivery is delayed
  • Shipping and receiving dock closed on weekends and holidays 
    • Deliveries accepted Monday - Friday 

Provide a pedigree, audiograms, clinic notes regarding hearing loss and temporal bone imaging studies (if performed).

 

Click here to print sample and shipping requirements.

Information

Quick Facts

  • CPT code: 81403
  • Test code: OTOSCFAM
  • Turnaround time: 6 weeks (excludes copy number variant detection)
  • Cost: $220
Requisition Form

To order:

Use this requisition form to order this test.

The Clinical Diagnostics Service of the Molecular Otolaryngology and Renal Research Laboratories is a Joint Commission-approved CLIA-accredited diagnostic laboratory.