Tests Included
The panel includes 21 tests:
- Complement levels (C3, C4, factor B, factor D, C5, Properdin, factor H, and factor I)
- Complement activation products (C3c, Ba, Bb, and Soluble C5b-9)
- Pathway activity assays (CH50, APFA, C3b Deposition Assay and fluid-phase activity assay)
- Detection of autoantibodies (Factor H autoantibodies, FB autoantibodies, C3Nefs, C4Nefs and C5Nefs)
MORL Screening Methodology
Functional assays, enzyme-linked immunosorbent assay (ELISA), turbidimetric assays and immunofixation electrophoresis (IFE) are utilized to assess the functionality and integrity of the complement system in patients with C3 Glomerulopathy.
Sample Requirements
Sample Requirements
Sample Stability
Sample Stability
- Serum and EDTA plasma samples must be frozen to below -80°C immediately after separation from cells and shipped on dry ice. These samples remain viable for at least six months when stored at -80°C.
Shipping Requirements
Shipping Requirements
- All serum and EDTA plasma samples MUST be processed and frozen down to -80°C immediately after collection
- Labeled with the sample type AND patient’s name, DOB, MRN and sex
- Sample type must be clearly labeled (either serum or EDTA plasma)
- Cryovials should be put in zip lock bags and completely covered in dry ice to keep the sample frozen until it arrives in the lab
- Shipped overnight on at least 5 lbs of dry ice
- Shipping and receiving dock closed on weekends and holidays
- Deliveries accepted Monday - Friday
If samples arrive thawed they will be REJECTED.
Quick Facts
- CPT codes: 86161(x5), 83516(x2), 86160(x11), 83520, 86162, 86334
- Test code: C3G-CP
- Turnaround time: 4 weeks
- Cost: $4847.40
*This cost represents a 10% discount over ordering each test in the panel a la carte.
The Clinical Diagnostics Service of the Molecular Otolaryngology & Renal Research Laboratories is a CLIA-approved, Joint Commission-accredited diagnostic laboratory.