Hearing impairment is the most frequent sensory defect in humans and is an economically and socially important cause of morbidity. Dramatic progress has been made in our understanding of the biology of hearing and deafness through the mapping of more than 120 loci and the identification of more than 41 genes.

Current Research

  • Hela Azaiez – Age-related hearing loss, noise-induced hearing loss, Mendelian hearing loss, genetic modifiers/promoters
  • Kevin Booth –  Mendelian hearing loss, Usher syndrome, genetic modifiers, non-coding mutations
  • Jin-Young Koh – RNA-seq and microRNA-based Therapeutic Approaches for Hearing Loss, Mendelian hearing loss and single-cell RNA sequence profiling
  • Diana Kolbe – Computational Analysis
  • Paul Ranum– Gene Therapy Approaches to Treat Dominant Progressive Hearing Loss, RNA interference, single cell transcriptomics
  • Hidekane Yoshimura– Viral-mediated RNA interference gene therapy

If you have hearing loss or you are a physician who has a patient with hearing loss and you are interested in evaluation for participation in our research studies please contact Amy Weaver (amy-weaver@uiowa.edu) or Dr. Richard Smith at richard-smith@uiowa.edu.

To be evaluated for research we require the following information:

  • A pedigree;
  • All available audiograms;
  • Clinical information related to your hearing loss;
  • Temporal bone imaging studies (if performed) report and images if available.

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