Hearing impairment is the most frequent sensory defect in humans and is an economically and socially important cause of morbidity. Dramatic progress has been made in our understanding of the biology of hearing and deafness through the mapping of more than 120 loci and the identification of more than 41 genes.
- Hela Azaiez – Age-related hearing loss, noise-induced hearing loss, Mendelian hearing loss, genetic modifiers/promoters
- Kevin Booth – Mendelian hearing loss, Usher syndrome, genetic modifiers, non-coding mutations
- Jin-Young Koh – RNA-seq and microRNA-based Therapeutic Approaches for Hearing Loss, Mendelian hearing loss and single-cell RNA sequence profiling
- Diana Kolbe – Computational Analysis
- Paul Ranum– Gene Therapy Approaches to Treat Dominant Progressive Hearing Loss, RNA interference, single cell transcriptomics
- Hidekane Yoshimura– Viral-mediated RNA interference gene therapy
If you have hearing loss or you are a physician who has a patient with hearing loss and you are interested in evaluation for participation in our research studies please contact Amy Weaver (firstname.lastname@example.org) or Dr. Richard Smith at email@example.com.
To be evaluated for research we require the following information:
- A pedigree;
- All available audiograms;
- Clinical information related to your hearing loss;
- Temporal bone imaging studies (if performed) report and images if available.
Other Web Sites:
- Data Sheet
- Deafness Variation Database
- Otolaryngology Home
- Hereditary Hearing Loss
- American Academy of Otolaryngology
- Association for Research in Otolaryngology
- Kresge Hearing Research Institute (lists WFS1 mutations)
- National Institute on Deafness and Other Communication Disorders Home Page
- Pendred/BOR Homepage