C3G Natural History Study: Assisting with the C3G Natural History study in development of a robust database of patients with C3 Glomerulopathy, with the goal of developing and validating useful predictive models of disease progression in a longitudinal data-driven analysis of clinical data, pathology and complement factors in C3G.  Our end goal is to establish a more complete understanding of disease progression to define treatable targets for this ultra-rare disease.

I am the genetic counselor for MORL Hearing Team and I am passionate about helping patients, families, and providers understand, adapt, and use genetic information about hearing loss. My clinical experience and genetic counseling training help inform my research projects which include: genotype/phenotype correlation for hearing loss genes, communication and use of genetic information for hearing loss for patients and providers, and translating information gained in our research to the clinical realm.

C3G Natural History Study
We are developing a robust database of patients with C3 Glomerulopathy with a goal to develop and validate useful predictive models of disease progression in a longitudinal data-driven analysis of clinical data, pathology and complement factors in C3G.  Our end goal is to establish a more complete understanding of disease progression to define treatable targets for this ultra-rare disease.

My primary focus as a member of the Clinical Diagnostic Service Functional Team is to look at the activity of autoantibodies in renal diseases.

I am a bioinformaticist working on genetic hearing loss research.  I build and use software pipelines to analyze sequencing data; perform statistical analyses of audiometric data; and develop and maintain web applications.

I currently run functional assays to measure complement activity and biomarker levels for patients. I also help with research by studying the functional effects of rare complement variants. 

I joined the MORL in December of 2013 and have over 17 years of molecular biology experience at the University of Iowa. My work in the Clinical Diagnostics Division focuses on the OtoScope panel to detect mutations related with hearing loss. Along with my colleagues, I prepare patient samples for next generation sequencing (NGS) and perform confirmation testing by Sanger sequencing.

I am a Research Associate working with the Functional Renal Team. Clinically I process complement tests to help clinicians to further understand their patients' complement-mediated renal diseases.  My research interest is studying acquired drivers of disease (autoantibodies to complement proteins).

I hold the title PWHWFRL (Person who has Worked for Richard Longest) and have just crossed the 15th year mark.  As a member of the Clinical Diagnostic Functional Renal Division I have become part vampire and like to bathe in sheep red blood cells as I determine which patients have autoantibodies that stabilize convertase.  With my two trusty 12 channel multi-pipetors in hand, and two water baths at my sides, I am a force to be reckoned with.

I am a computational specialist working with our teams on genetic diagnosis and research. Once the DNA from a sample has been sequenced, I transform that data into lists of genetic changes that each person has, and then I help our team sort through those lists and narrow down to the ones that could cause the symptoms.