Yuzhou Zhang
Senior Research Scientist (Functional Renal)
Person Type: 

I am the team lead of the functional diagnostic group in the Molecular Otolaryngology and Renal Research Laboratories. The lab offers unique complement tests to help clinicians / patients to understand complement-mediated renal diseases. My team performs routinely many lab-developed tests and reports results within a short turnaround time.

 My area of research interest includes identifying novel biomarkers for two closely related diseases, Dense Deposit Disease (DDD) and C3 Glomerulonephritis (C3GN). And use new biomarkers to understand disease pathology and to followup disease course during therapeutic trials. Another area of research interest is to study acquired drivers of disease - autoantibodies to complement proteins - to define how they cause DDD, C3GN and atypical Hemolytic Uremic Syndrome (aHUS), and to which complement proteins they develop. My third area of interest is, through national and international collaborations, to create and test new therapeutics for complement-mediated renal diseases using our extensive biorepository and also our murine models.