The Clinical Diagnostics Service of the Molecular Otolaryngology and Renal Research Laboratories is a CLIA-approved, Joint Commission-accredited diagnostic laboratory.
Plasma Factor H Level
Dense Deposit Disease, C3 Glomerulonephritis and atypical Hemolytic Uremic Syndrome
Complement Factor H (FH; MW: 155 kDa) is an important fluid-phase and cell-surface regulator of alternative pathway (AP) activity. Patients with FH mutations or FH autoantibodies may have reduced plasma FH levels and/or function, and are at-risk to develop atypical hemolytic uremic syndrome or C3 glomerulopathy.
Indications for screening
Testing is appropriate for patients with DDD, C3GN and aHUS.
MORL screening methodology
Radial immunodiffusion (RID)
Turnaround time is ~2 weeks.
1 ml frozen EDTA plasma (please see testing requisition for specimen handling).
Cost & CPT Codes
See the MORL testing menu