Genes Included in Genetic Renal Panel v8

• CFH (Complement Factor H)
• CFI (Complement Factor I)
• MCP (Membrane Co-Factor Protein or CD46)
• CFB (Complement Factor B)
• CFHR5 (Complement Factor H Related 5)
• THBD (Thrombomodulin)
• C3 (Complement Component 3)
• ADAMTS13 (A Disintegrin and Metalloproteinase with a Thrombospondin Type 1 Motif, Member 13)
• PLG (Plasminogen)
• DGKE (Diacylglycerol Kinase, Epsilon)
• MMACHC (Metabolism of Cobalamin Associated C)
• G6PD (Glucose-6-Phosphate Dehydrogenase)
• WT1 (WT1 Transcription Factor)
• C5 (c.2653C>T, p.Arg885Cys and c.2654G>A, p.Arg885His) - two single nucleotide variants that could compromise responsiveness to Eculizumab

Multiplex ligation-dependent probe amplification (MLPA) is included in the testing to determine copy number variants over the CFH-CFHR5 genomic region.

Cost & CPT Codes

• MORL Testing Menu
• Clinical Kidney Testing Requisition Form

The Clinical Diagnostics Service of the Molecular Otolaryngology & Renal Research Laboratories is a CLIA-approved, Joint Commission-accredited diagnostic laboratory.