The first truly comprehensive genetic test for hereditary hearing loss, Usher syndrome, and Pendred syndrome.
- For a scientific manuscript describing the first OtoSCOPE® study, click here.
- For a copy of our current OtoSCOPE® brochure, click here.
In the past, persons diagnosed with hereditary hearing loss often required multiple tests to determine the exact cause of their hearing loss. These tests could be expensive, inconvenient, and time consuming. Now, The University of Iowa offers OtoSCOPE® (version 8) -- one test that is:
- Comprehensive – tests for 152 genes known to cause non-syndromic hearing loss, Usher syndrome, and Pendred syndrome and other hearing loss-related phenotypes. It investigates both single nucleotide variants and copy number variations (deletion/duplication analysis).
- Easy – patient provides one blood sample
- Convenient – blood sample is taken in local doctor’s office
- Fast – one test shortens waiting time for results
- Accurate – 99 percent diagnostic specificity
- Pinpointed diagnosis – offers the best method of genetic diagnosis; prognosis for additional hearing issues; and potential genetic counseling
- Less expensive – one test versus many tests
Next Generation Sequencing and Read Depth Analysis (for deletion/duplication analysis).
Turnaround time is approximately 2 months.
8 - 10 cc. whole blood in lavender (EDTA) top tubes OR 10 μg DNA, minimum concentration: 50 ng/μl (A260/A280 1.8-2) resuspended in 0.1mM EDTA (10mM Tris HC1, 0.1mM EDTA, pH 8, Teknova Cat#T0220).
Cost & CPT Codes
See the MORL Testing Menu