PDF iconMORL 2020 Hearing Loss Test Requisition Form (Effective January 3, 2020)

The first truly comprehensive genetic test for hereditary hearing loss, Usher syndrome, and Pendred syndrome.

  • For a scientific manuscript describing the first OtoSCOPE® study, click PDF iconhere.
  • For a copy of our current OtoSCOPE® brochure, click PDF iconhere.

In the past, persons diagnosed with hereditary hearing loss often required multiple tests to determine the exact cause of their hearing loss. These tests could be expensive, inconvenient, and time consuming. Now, The University of Iowa offers OtoSCOPE® (version 8) -- one test that is:

  • Comprehensive – tests for 152 genes known to cause non-syndromic hearing loss, Usher syndrome, and Pendred syndrome and other hearing loss-related phenotypes.  It investigates both single nucleotide variants and copy number variations (deletion/duplication analysis).
  • Easy – patient provides one blood sample
  • Convenient – blood sample is taken in local doctor’s office
  • Fast – one test shortens waiting time for results
  • Accurate – 99 percent diagnostic specificity
  • Pinpointed diagnosis – offers the best method of genetic diagnosis; prognosis for additional hearing issues; and potential genetic counseling
  • Less expensive – one test versus many tests

Next Generation Sequencing and Read Depth Analysis (for deletion/duplication analysis).

Turnaround time: 
Turnaround time is approximately 2 months.

Sample Required:
8 - 10 cc. whole blood in lavender (EDTA) top tubes OR 10 μg DNA, minimum concentration: 50 ng/μl (A260/A280 1.8-2) resuspended in 0.1mM EDTA (10mM Tris HC1, 0.1mM EDTA, pH 8, Teknova Cat#T0220).

Cost & CPT Codes 
See the MORL Testing Menu

GeneTests GeneReviews - Deafness and Hereditary Hearing Loss Overview